A recent study has found that three mutations in the Epsilon coronavirus spike protein dampen the neutralizing potency of antibodies induced by current vaccines or past COVID infections: https://newsroom.uw.edu/news/epsilon-variant-mutations-contribute-covid-immune-evasion. Read the full research paper here: https://science.sciencemag.org/content/373/6555/648?rss=1. However, it should be noted that despite these early studies, previous studies have shown vaccines work against “variants of concern,” such as the Delta variant. The vaccines also prevent serious illness, hospitalization and death in most cases where a fully vaccinated person catches COVID-19.